Browsing by Author "Senthil Amudhan, M."
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Item Antimicrobial activities of polyphenol extract of arecanut against pathogenic bacteria(2012) Senthil Amudhan, M.Item Antioxidant activity and biochemical profile of cocoa clones(2016) Senthil Amudhan, M.; Elain Apshara, S.Item Biochemical Components of Cocoa and their Benefits on Human Health(2012) Senthil Amudhan, M.; Elain Apshara, S.Item A comparative study on antioxidant activity and biochemical profile of exotic cocoa (Theobroma cacao L.) clones(2015-12) Senthil Amudhan, M.; Elain Apshara, S.Item INHIBITORY EFFECT OF ARECANUT EXTRACT ON H2 O2 INDUCED RBC HAEMOLYSIS(2006) Senthil Amudhan, M.; Hazeena BegumItem PHARMACOLOGICAL EFFECTS OF ARECANUT(2005) Senthil Amudhan, M.Item PHCOG MAG.:Reaserch article Alpha glucosidase inhibitory and hypoglycemic activities of areca catechu extract(PHCOG MAG, 2008-09) Senthil Amudhan, M.; Hazeena Begum, V.Item Protective Effect of Areca Catechu Extract on Ethanol Induced Gastric Mucosal Lesions in Rats(2008) Senthil Amudhan, M.; Hazeena Begum, V.In the present study, the antiulcerogenic activity of defatted ethanol extract of Areca catechu was investigated. Ethanol treatment significantly increased the levels of gastric mucosal malondialdehyde (MDA, an index of lipid peroxidation), nitric oxide (NO) and increase in the activities of myeloperoxidase (MPx, an index neutrophil infiltration) and xanthine oxidase (XO) enzymes. Pretreatment with A. catechu in the doses of 250mg/kg and 500mg/kg body weight, prevented the formation of gastric mucosal MDA, NO contents and activities of MPx and XO. Ethanol induction also showed a significant reduction of the gastric mucosal glutathione (GSH), sialic acid and deoxyribo nucleic acid (DNA) levels. The pretreatment with A. catechu maintained the levels similar to normal control level. Based on these data, the protective effects of both 250mg/kg and 500mg/kg doses of A. catechu on ethanol induced gastric mucosal injury may be attributed to its antioxidant effect.