Role of Areca Nut Consumption in the Cause of Oral Cancers

Simple item page
dc.contributor.authorBhavana J. Dave
dc.contributor.authorAmit H. Trivedi
dc.contributor.authorSiddharth G. Adhvaryu
dc.date.accessioned2014-09-16T04:25:36Z
dc.date.available2014-09-16T04:25:36Z
dc.date.issued1992
dc.description.abstractBackground. Cytogenetic studies, framed to assess the. possible genomic: damage caused by areca nut consumption (without tobacco and not as a component of betel quid), were performed among areca nut chewers which included normal people who chew areca nuts, patients with oral submucous fibrosis, and patients with oral cancer, and healthy nonchewing controls. Results. The analysis showed statistically significant increases in the frequencies of sister chromatid exchanges and chromosome aberrations in peripheral blood lymphocytes and the percentage of micronucleated cells in exfoliated cells of buccal mucosa among all three groups of chewers when compared with those of the controls. Conclusions. The current data, the first of this type among only areca nut chewers, highlight that this popular masticatory is erroneously considered "safe" and that it increases the genomic damage even when chewed without tobacco. The data also signify that, henceforth, in cytogenetic biomonitoring, areca nut consumption also should he considered as one of the confounding factors.en_US
dc.identifier.citationCancer, September 1992,Vol.70 No.5en_US
dc.identifier.urihttp://hdl.handle.net/123456789/5739
dc.language.isoenen_US
dc.subjectareca nut consumptionen_US
dc.subjectgenotoxicityen_US
dc.subjectoral cancersen_US
dc.subjectcytogenetic studyen_US
dc.subjectCAen_US
dc.subjectSCEen_US
dc.subjectMNCen_US
dc.titleRole of Areca Nut Consumption in the Cause of Oral Cancersen_US
dc.typeArticleen_US

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
role of areca nut consumption in the cause of oral cancers.pdf
Size:
3.43 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Reprints