Subunit structure of the vicilin-like globular storage protein of cocoa seeds and the origin of cocoa- and chocolate-specific aroma precursors

dc.contributor.authorUlrich Kratzer
dc.contributor.authorRonald Frank
dc.contributor.authorHubert Kalbacher
dc.contributor.authorBole Biehl
dc.contributor.authorJohannes Wostemeyer
dc.contributor.authorJurgen Voigt
dc.date.accessioned2014-04-17T11:13:52Z
dc.date.available2014-04-17T11:13:52Z
dc.date.issued2009
dc.description.abstractEssential cocoa-specific aroma precursors are generated during fermentation of cocoa seeds by proteolysis of the vicilin-like globulin. This particular storage protein consists of three subunits with apparent molecular masses of 47 kDa, 31 kDa, and 15 kDa, respectively, which are derived from a common 66- kDa precursor. Since all these subunits resist N-terminal sequencing by Edman degradation, we have analysed the localisation of these vicilin subunits on their common precursor sequence by MALDI-TOF-MS analyses of their tryptic fragments. The results were corroborated by epitope mapping of polyclonal antibodies using 185 overlapping pentadeca-peptides covering the whole sequence of the precursor. The results show that the cocoa vicilin is encoded by a single gene and that heterogeneity of the vicilin subunits must be attributed to statistical post-translational modifications. Localisation of the precursor regions, from which the various subunits are derived, will be helpful for the future identification of aroma-relevant peptides generated during the fermentation process.en_US
dc.identifier.citationFood Chemistry 113 (2009) 903–913en_US
dc.identifier.urihttp://hdl.handle.net/123456789/427
dc.language.isoenen_US
dc.subjectCocoa seedsen_US
dc.subjectEpitope mappingen_US
dc.subjectMALDI-ReTOF-MSen_US
dc.subjectStorage proteinen_US
dc.subjectTheobroma cacaoen_US
dc.subjectVicilinen_US
dc.titleSubunit structure of the vicilin-like globular storage protein of cocoa seeds and the origin of cocoa- and chocolate-specific aroma precursorsen_US
dc.typeArticleen_US

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