Shashwati GhoshAshish SachanAdinpunya Mitra2014-05-022014-05-022006Current Science, Vol. 90, No. 6, 25 March 2006http://hdl.handle.net/123456789/831A filamentous fungus Paecilomyces variotii MTCC 6581 was analysed for its capability to transform ferulic acid into vanillate derivatives. When cultures of P. variotii were grown on minimal medium containing ferulic acid (10 mM) as sole carbon source, formation of vanillic acid was observed. In this case, a maximum amount of 115 mg/l of vanillic acid was accumulated after 16 days of incubation. Glucose supplementation (0.1% w/v) in the minimal medium resulted in an increased production of vanillic acid (226 mg/l), whereas with starch supplementation, a decrease in the accumulation of vanillic acid (85 mg/l) was observed. In vitro conversion of ferulic acid to vanillic acid was also demonstrated with cell-free extract.enFerulic acidPaecilomyces variotiivanillinvanillic acidArticle