Efficient Synthesis of (±)-4-Methyloctanoic Acid, Aggregation Pheromone of Rhinoceros Beetles of the Genus Oryctes (Coleoptera: Dynastidae, Scarabaeidae)

Valentine RagoussisAlexandros GiannikopoulosEfthymia SkokaPanagiotis Grivas2014-06-172014-06-172007J. Agric. Food Chem. 2007, vol.55(13) pp.5050-5052http://hdl.handle.net/123456789/2989(±)-4-Methylocttinoic acid and its ethyl ester are aggregation pheromones of many rhinoceros beetles of the genus Oryctes and are investigated for the control of these pests by olfactorj trapping. A simple, economical, and high-yield (>50%) synthesis of (±)-4-methyloctanoic acid and its ethyl ester is presanted starting from n-hexanal. The key stefJ in this sequence is an orthoester Clalsen rearrangement for the elongation of the carbon chain by two.enPheromone synthesisrhinoceros beetlesOryctes elegansOryctes rhinocerosOryctes monoceros4-methyloctanoic acidethyl-4-methyloctanoateClaisen rearrangementEfficient Synthesis of (±)-4-Methyloctanoic Acid, Aggregation Pheromone of Rhinoceros Beetles of the Genus Oryctes (Coleoptera: Dynastidae, Scarabaeidae)Article